Raphael Z Sangeda
I am a senior lecturer at the Muhimbili University of Health and Allied Sciences (MUHAS) in Dar es Salaam, Tanzania. I work in the department of Pharmaceutical Microbiology, where I give lectures and supervise Microbiology practical at undergraduate and postgraduate levels. I also serve as a visiting lecturer in Bioinformatics at African Institute of Mathematical Sciences in Bagamoyo, Tanzania, and the University of Dar es Salaam, Tanzania.
I participate in the H3ABioNet: a sustainable African Bioinformatics Network for H3Africa. H3ABioNet is the consortium of Pan African Bioinformatics network for H3Africa (Human Heredity and Health in Africa), for which I serve as the bioinformatician. I also participate in the Sickle PanAfrican Research Consortium (SPARCO), a consortium of three countries (Ghana, Nigeria, and Tanzania), for which I serve as database manager and co-investigator. I am a member of the Tanzania Genome Network, which collects and analyzes genetic information to improve the prognosis of diseases, such as malaria, HIV, TB, diabetes, mental illness, neurological diseases, cancer, and sickle cell disease.
My interests are to apply bioinformatics and informatics skills in order to store, retrieve, analyze, and correlate the genetic markers of these diseases with respect to the unique heredity profile of the population. The techniques involved in generating genetic information range from ‘classical genotyping’ methods to ‘next generation’ sequencing, all generating massive amounts of genotypic data, which have become widely available in resource-constrained countries in Africa. Moreover, I wish to participate in building human capacity and infrastructure, including training personnel how to handle these complex data and their application to disease burden alleviation. This extends beyond genetic data alone to also include collecting phenotypic data from individual patients.